IPN-LIKE, A UNIQUE AND PATENTED TECHNOLOGY

In 2007, Laboratoires VIVACY patented the IPN-Like Technology, the advanced hyaluronic acid cross-linking process that makes it possible to design high performance products with special properties for medical and aesthetic applications.

All STYLAGE® monophasic cross-linked injectable gels are based on IPN-Like Technology, characterized by the unique viscoelastic properties and superior tissue biocompatibility.

stylage ipn-like

ADVANTAGES OF IPN-LIKE TECHNOLOGY

SUPERIOR LIFTING CAPACITY

All STYLAGE® products are carefully designed for injection into different dermal layers to support different aesthetic applications. The gels are characterized by two key parameters:

The elasticity of each product is optimized according to the intended indication: lower for fine lines and superficial wrinkles,
higher for deep wrinkles or thicker skin.

The viscosity of each STYLAGE® gel is adapted to match the density of the target tissue for which it is intended, resulting in a long-lasting aesthetic enhancement.

Thus, the versatile STYLAGE® range allows the practitioner to optimize the aesthetic effect for each individual patient.

BIODEGRADABLE PRODUCTS

STYLAGE® products consist of an ultra-clear transparent gel of cross-linked hyaluronic acid. The gel is biocompatible and readily becomes integrated into the tissue. It is non-permanent, i.e. it is biodegraded by the body’s own mechanism and will thus disappear naturally over time*.

*The average product duration depends on many factors such as skin type, injection area, patient’s lifestyle, injection technique used by the practitioner.

stylage ipn-like

ANTIOXIDANT BENEFITS

All STYLAGE® products are exclusively formulated with antioxidants, mannitol or sorbitol.

Mannitol is an antioxidant agent found in a large variety of fruits, vegetables and plants. It is widely used in the pharmaceutical industry and has been incorporated into STYLAGE® gels to preserve physico-chemical properties of the injected hyaluronic acid.

Protective action

When a needle is inserted into the skin tissue, the inflammatory response includes activation of free radical-generating enzymes on the injection site. Those reactive molecules attack the injected HA and try to break down its overall structure. Antioxidants, free radical scavenger, are helpful in reducing and preventing damage from free radical reactions because of their ability to neutralize the radical without forming another. They provide optimal resistance to the gel’s degradation. They also help stabilize physico-chemical properties of the product in the syringe during its storage at room temperature.

Sorbitol, like mannitol, is an antioxidant agent that has been safely used in cosmetics and beauty products for a long time due to its powerful moisturizing properties. Complementary to the STYLAGE® range with mannitol, sorbitol has been added to STYLAGE® HydroMax formulation, a dermal filler specifically developed by Laboratoires VIVACY to improve skin hydration and elasticity. As a very hygroscopic antioxidant, sorbitol helps skin retain water to conserve moisture and thereby keeps it looking healthy and youthful.

stylage ipn-like

COMPLIANCE WITH INTERNATIONAL SAFETY STANDARDS

All STYLAGE® products are designed and manufactured by Laboratoires VIVACY in France. Product and customer safety is of paramount concern at Laboratoires VIVACY. Production, quality control, quality assurance and regulatory teams work together to achieve this goal and to provide the consistently safe, high-quality products and services all over the world.

Laboratoires VIVACY has been using European Pharmacopoeia high purity medical injection grade hyaluronic acid obtained by biofermentation and of non-animal origin for the manufacture of all STYLAGE® medical devices.

  • Rigorous selection of raw materials provided by recognized European manufacturers.
  • Careful manual control of each syringe by specially-trained operators.
  • Regular audits of legal authorities and suppliers.
  • Qualification of manufacturing process.
  • Control of work areas: ISO Class 7 Clean Room, ISO 5 flow.
  • High level of staff training.